converting concept into product

Discovering opportunities, accelerating development and partnering wisely

About Us

Greenfire Bio (GFB)

GFB is an oncology focused clinical stage biopharma company that looks to collaborate with, in-license or acquire early-stage assets and develop them through clinical proof-of-concept and beyond. As we access new assets, we set up new subsidiaries to provide the focus required to advance these into and through the clinic.

How we build success

Medical innovations are precious and exciting and come from all over. Making a good idea in medicine into a product is a difficult and expensive process. It requires expertise and capital often not available for startups completing laboratory proof-of-concept.

That’s where Greenfire comes in. We have assembled highly experienced team of pharmaceutical experts bolstered by a network of advisors and service providers to deploy on late pre-clinical and early clinical assets to accelerate their development into products.

Our extensive network seeks out exciting innovations, engages flexibly with innovators, and accelerates the transition to medical products. We take the unappreciated risks out of development – timely access to expertise and capital. If you think you have an innovation that fits our profile, contact us.

status

Since the inception of the company in 2020, the company has acquired a first-in-class small molecule SIK2/3 inhibitor (GRN300) currently in a Ph1 trial, invested in a company called Pacylex that has a first-in-class NMT1/NMT2 inhibitor (PCLX001) in Ph1 testing for hematological malignancies and in-licensed a novel therapeutic vaccine platform (M-001-004) for solid tumors from the Mayo Clinic that has undergone Ph1 testing. GFB has set up operating subsidiaries for the SIK2/3 inhibitor (Green3Bio) and the therapeutic vaccine products (MGFB Bio).

Opportunity Access

Capitalize on access to innovative preclinical and early-stage clinical products and technology

Development Acceleration

Leverage an integrated ecosystem of development organizations and internal expertise to accelerate product development timelines

Business MONETIZATION

Monetize investments through strategic and well-timed out-licensing, sale or IPO of each product to provide liquidity to investors and the best path to bringing products to patients

Our process sounds simple but execution is where we excel

Acquire pipeline of differentiated products to meet underserved medical needs. If you think you have an innovation that fits our profile, contact us.

Deploy very experienced biopharma team for efficient drug development and business management

Utilize a successful organizational model; leverage virtual operations focused program management and partner ecosystem of service providers

Exit programs after advancing candidates to an appropriate value inflection point

Provide excellent returns to investors by delivering superior products to patients

MANAGEMENT TEAM

Ajit Gill

CEO and Founder, Director

CEO & President Nektar Therapeutics
VP and Gen Mgr Kodak’s Interactive Systems
VP Finance at TRW-Fujitsu

Sanjeev Munshi, PHD, MBA

Consultant, Business Development

SVP, BD & Alliance Management, InveniAI
Ex. Director Merck BD and Discovery

Vikas Agarwal, PhD

Consultant Program Management

J. Andrew Sanford, MBA

Consulting CFO

Markus Peter

Consultant, Program Lead GRN-300

Chris Searcy, Consultant, Corporate Development

CBO Nocion
CBO Respira
CBO Taris
VP Valeritas, Nektar, Pfizer

BOARD OF DIRECTORS

J. Andrew Sanford, MBA

Consulting CFO

Ajit Gill

Director

Chris Searcy, Consultant, Corporate Development

CBO Nocion
CBO Respira
CBO Taris
VP Valeritas, Nektar, Pfizer

Hong-Min Suh

Chair, M2N
CEO, DK Marine
Chair, The LEADCORP

Sang Hoon Shin

PIPELINE

Making a fast start to building an innovative pipeline, agnostic to therapeutic areas, we are addressing serious unmet medical needs.
If you think you have an innovation that fits our business strategy, contact us.

*Click for more information about portfolio candidates

Products Company Target Indication Therapeutic Area Discovery Preclinical Clinical
In Vitro In Vivo Lead Op IND Enabling Phase 1 Phase 2
GRN-300 Green3Bio SIK2/SIK3 inhibitor (First-in-Class) Ovarian cancer, TNBC Oncology

M-001
M-002
M-003
M-004
MGFB¹
Heteroclitic
Epitope
Activated
Therapy
Melanoma
Glioma
Colorectal Cancer
Hepatocellular Carcinoma
Solid Tumors
PCLX-001 Pacylex² NMT1, NMT2 inhibitor (First-in-class)

Diffuse B-Cell Lymphoma (DLBCL)

Acute Myeloid Leukemia (AML)

Oncology
¹A subsidiary of Fairwinds Bio based on technology licensed from Mayo Clinic.
²Investment

Questions?   We’ve got answers!

Latest Articles

MGFB: Vaccinating Against Tumor Antigen Escape

MGFB: Vaccinating Against Tumor Antigen Escape

The Greenfire Bio subsidiary is developing xenogenic tumor antigen libraries delivered via engineered viruses. Article by Richard Guy, Biopharma Analyst MGFB is developing virus-based cancer vaccines for solid tumors that prime the immune system against hundreds of tumor antigens, including ones...

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